Antibacterial agent 132
Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of aromatase enzyme with an IC50 of 0.047μM[1].
Product Specifications
CAS Number
[3026790-18-8]
UNSPSC
12352005
Target
Bacterial; Cytochrome P450
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-132.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C2N=C(C(/C=N/NC3=NC(C4=CC=CC(F)=C4)=CS3)=CC2=C1)Cl
Molecular Formula
C20H14ClFN4OS
Molecular Weight
412.87
References & Citations
[1]Asaf Evrim Evren, et al. Investigation of Novel Quinoline-Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches. ACS Omega. 2022 Dec 29;8 (1) :1410-1429.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aromatase/CYP19A1
Available Sizes
Curated Selection
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