Antibacterial agent 132

Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of aromatase enzyme with an IC50 of 0.047μM[1].

Product Specifications

CAS Number

[3026790-18-8]

UNSPSC

12352005

Target

Bacterial; Cytochrome P450

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-132.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C2N=C(C(/C=N/NC3=NC(C4=CC=CC(F)=C4)=CS3)=CC2=C1)Cl

Molecular Formula

C20H14ClFN4OS

Molecular Weight

412.87

References & Citations

[1]Asaf Evrim Evren, et al. Investigation of Novel Quinoline-Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches. ACS Omega. 2022 Dec 29;8 (1) :1410-1429.