FUBP1-IN-2
Product Specifications
UNSPSC Description
FUBP1-IN-2 (compound 9) is a potent FUBP1 (far upstream binding protein 1) inhibitor. FUBP1-IN-2 inhibits the KH4 FUBP1-FUSE interaction in a gel shift assay. FUBP1-IN-2 binds to FUBP1 in a ChIP assay. FUBP1-IN-2 reduces both c-Myc mRNA and protein expression, increases p21 mRNA and protein expression, and depletes intracellular polyamines[1].
Target Antigen
c-Myc
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fubp1-in-2.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C(NC2=C(C=C(C=C2)N3CCN(CC3)C4=C(C=CC(Cl)=C4)C)C(O)=O)=O
Molecular Weight
479.96
References & Citations
[1]Dobrovolskaite A, et al. Discovery of Anthranilic Acid Derivatives as Difluoromethylornithine Adjunct Agents That Inhibit Far Upstream Element Binding Protein 1 (FUBP1) Function. J Med Chem. 2022 Nov 24;65(22):15391-15415.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151884/FUBP1-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151884/
Clinical Information
No Development Reported
CAS Number
1242862-71-0
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