Icotinib-d4
Icotinib-d4 is the deuterium-labeled Icotinib (HY-15164A) . Icotinib-d4 (BPI-2009) is a potent and specific EGFR inhibitor with an IC50 of 5 nM; also inhibits mutant EGFRL858R, EGFRL858R/T790M, EGFRT790M and EGFRL861Q. Icotinib-d4 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[1567366-82-8]
Product Name Alternative
BPI-2009-d4
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
[2H]C1([2H])C([2H])([2H])OCCOC2=CC(C(NC3=CC(C#C)=CC=C3)=NC=N4)=C4C=C2OCCO1
Molecular Formula
C22H17D4N3O4
Molecular Weight
395.44
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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