SEH inhibitor-10
SEH inhibitor-10 (Compound 37) is a selective soluble epoxide hydrolase (sEH) inhibitor (IC50=0.5 μM) . sEH inhibitor-10 maintains high cycloeicosatrienoic acid (EETs) levels by inhibiting sEH, thereby reducing inflammation, regulating endothelial tone, improving mitochondrial function, and reducing oxidative stress. sEH inhibitor-10 has good research potential in metabolic, renal and cardiovascular diseases[1].
Product Specifications
UNSPSC
12352005
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/seh-inhibitor-10.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(N=C(SCC2=CC=CC=C2C(F)(F)F)N3)=C(C=C1)C3=O)NCC(C)(C)C
Molecular Formula
C22H22F3N3O2S
Molecular Weight
449.49
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151616/sEH-inhibitor-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151616/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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