Autophagy-IN-2

Autophagy-IN-2 (Compound 7h) is an autophagic flux inhibitor. Autophagy-IN-2 induces cancer cell apoptosis and can be used for triple-negative breast cancer research[1].

Product Specifications

CAS Number

[2755454-90-9]

UNSPSC

12352005

Target

Apoptosis; Autophagy

Type

Reference compound

Related Pathways

Apoptosis; Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/autophagy-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C2=NC3=CC=CC=C3N2)N=CN1)NC4CCCCC4

Molecular Formula

C17H19N5O

Molecular Weight

309.37

References & Citations

[1]Yang DL, et al. Discovery of fused benzimidazole-imidazole autophagic flux inhibitors for treatment of triple-negative breast cancer. Eur J Med Chem. 2022 Jun 26;240:114565.