ODN D-SL03
Product Specifications
UNSPSC Description
ODN D-SL03 is a C class CpG oligonucleotides, can induce stimulate PBMCs to produce high level of IFN-α. ODN D-SL03 can activate human B cells, NK cells and mononuclear cells and up-regulate expression of CD80, CD86 and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 also can inhibit the growth of the tumor. ODN D-SL03 sequence: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'[1].
Target Antigen
IFNAR
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/odn-d-sl03.html
Purity
99.82
Solubility
H2O : ≥ 20 mg/mL
Smiles
[DNA, d(P-thio)(T-C-G-C-G-A-A-C-G-T-T-C-G-C-C-G-C-G-T-T-C-G-A-A-C-G-C-G-G)]
Molecular Weight
9345.00
References & Citations
[1]Yang L, et al. CpG oligodeoxynucleotides with double stem-loops show strong immunostimulatory activity. Int Immunopharmacol. 2013 Jan;15(1):89-96.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150749/ODN-D-SL03-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150749/ODN-D-SL03-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1198621-85-0
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