HDAC6-IN-12
HDAC6-IN-12 (compound GZ) is a potent HDAC6 inhibitor. HDAC6-IN-12 has anticancer activity through merges into DNA strands causing DNA damage. HDAC6-IN-12 can be used for cancer research[1].
Product Specifications
CAS Number
[2803866-44-4]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac6-in-12.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCC(NC(C=CN1[C@@H]2O[C@H](CO)[C@H](C2(F)F)O)=NC1=O)=O
Molecular Formula
C24H39F2N3O5
Molecular Weight
487.58
References & Citations
[1]Li Y, et, al. Design, synthesis and antitumor activity study of a gemcitabine prodrug conjugated with a HDAC6 inhibitor. Bioorg Med Chem Lett. 2022 Sep 15;72:128881.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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