c-Met-IN-13
Product Specifications
UNSPSC Description
c-Met-IN-13 is a potent c-Met inhibitor with an IC50 value of 2.43 nM. c-Met-IN-13 shows excellent cytotoxicity for cancer cells. c-Met-IN-13 shows antiproliferative activity in a concentration- and time- dependent manner. c-Met-IN-13 has the potential for the research of cancer[1].
Target Antigen
c-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-met-in-13.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C(C)(C)C)C(NC1=CC=C(OC2=CC=NC3=CC(OC)=C(OC)C=C23)C(F)=C1)=O)C4=CC=C(F)C=C4
Molecular Weight
550.55
References & Citations
[1]Nan X, et al. Structure-based discovery of novel 4-(2-fluorophenoxy)quinoline derivatives as c-Met inhibitors using isocyanide-involved multicomponent reactions. Eur J Med Chem. 2020 May 1;193:112241.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150576/c-Met-IN-13-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150576/
Clinical Information
No Development Reported
CAS Number
2377724-93-9
Curated Selection
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