α-Glucosidase-IN-11
Product Specifications
UNSPSC Description
α-Glucosidase-IN-11 is a highly permeable competitive α-glucosidase inhibitor with the IC50 value of 0.56 μM. α-Glucosidase-IN-11 binds to Trp residues in α-glucosidase and regulates protein folding. α-Glucosidase-IN-11 can be used to regulate blood glucose levels[1].
Target Antigen
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-11.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC)C1=CC=C(N2C(CO)=CC=C2/C=C3OC(C4=C\3C=C(C)NC4=O)=O)C=C1
Molecular Weight
420.41
References & Citations
[1]Tania Luthra, et al. Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes. Eur J Med Chem. 2020 Feb 15;188:112034.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150560/α-Glucosidase-IN-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150560/
Clinical Information
No Development Reported
CAS Number
2411744-76-6
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