PI3K-IN-38
Product Specifications
UNSPSC Description
PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].
Target Antigen
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pi3k-in-38.html
Solubility
10 mM in DMSO
Smiles
CC1(C)OCCN2C1=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C23
Molecular Weight
380.44
References & Citations
[1]Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150034/PI3K-IN-38-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150034/
Clinical Information
No Development Reported
CAS Number
1382979-64-7
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