Phosphodiesterase-IN-1
Product Specifications
UNSPSC Description
Phosphodiesterase-IN-1 (Compound 7) is a phosphodiesterase (PDE) inhibitor with anti-Plasmodium activity. Phosphodiesterase-IN-1 has antiproliferative activity against P. falciparum (strain 3D7) with an IC50 value of 0.64 μM[1].
Target Antigen
Parasite; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/phosphodiesterase-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(CC2=CC=C(C=C2)F)NC3=C1NN=C3C(C)C
Molecular Weight
286.30
References & Citations
[1]Howard BL, et al. Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites. ACS Chem Biol. 2015 Apr 17;10(4):1145-54.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149782/Phosphodiesterase-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149782/
Clinical Information
No Development Reported
CAS Number
521297-42-7
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