B3GNT2-IN-1
Product Specifications
UNSPSC Description
B3GNT2-IN-1 (compound 8j) is a β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) inhibitor, with an IC50 of 9 nM[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/b3gnt2-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=CC=C(C=C2N1[C@@H](C(C)(C)C)C)C(N[C@@](C3=CN=C(N=C3)C(F)(F)F)4C)=NC4=O
Molecular Weight
460.45
References & Citations
[1]Jackson JJ, et al. Imidazolone as an Amide Bioisostere in the Development of β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors. J Med Chem. 2023 Dec 14;66(23):16120-16140.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149777/B3GNT2-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149777/
Clinical Information
No Development Reported
CAS Number
3033557-95-5
Curated Selection
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