Ferroptosis-IN-4
Product Specifications
UNSPSC Description
Ferroptosis-IN-4 (compound 6k) is a ferroptosis inhibitor with EC50 value of 20 μM. Ferroptosis-IN-4 has no obvious cytotoxicity. Ferroptosis-IN-4 has a protective effect in glycerol-induced RM-AKI mice with alleviating kidney dysfunction[1].
Target Antigen
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ferroptosis-in-4.html
Solubility
10 mM in DMSO
Smiles
CN(CCN(C)C)C1=CC=C(N2C(C)=C(O)C(C=C2)=O)C=C1.Cl
Molecular Weight
337.84
References & Citations
[1]Jie Cen, et al. Synthesis and structure-activity optimization of hydroxypyridinones against rhabdomyolysis-induced acute kidney injury. Eur J Med Chem. 2023.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149719/Ferroptosis-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149719/
Clinical Information
No Development Reported
CAS Number
2798922-35-5
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