UCM-13207
UCM-13207 (compound 21) is a selective ICMT inhibitor that ameliorates basic progeria-like features. UCM-13207 can improve the survival rate of LmnaG609G/G609G mice in the mouse premature aging model[1].
Product Specifications
CAS Number
[1621536-10-4]
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ucm-13207.html
Purity
99.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCN(CCCCCCCC)C(C1=CC=CC=C1)=O)NC2=CC=CC=C2
Molecular Formula
C24H32N2O2
Molecular Weight
380.52
References & Citations
[1]Marcos-Ramiro B et al. Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome[J]. ACS Central Science, 2021, 7 (8) : 1300-1310.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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