α-Glucosidase-IN-42

α-Glucosidase-IN-42 (Compound 26) is a 9-O-berberrubine carboxylate derivative. α-Glucosidase-IN-42 has potent α-glucosidase inhibitory activities with an IC50 value in the range of 1.61 μM. α-Glucosidase-IN-42 can be used for the research of antidiabetic[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-42.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C2C=C3[N+](CCC4=C3C=C(OCO5)C5=C4)=CC2=C1OC(C6=CC(C(C)(C)C)=CC(C(C)(C)C)=C6)=O.[Cl-]

Molecular Formula

C34H36ClNO5

Molecular Weight

574.11

References & Citations

[1]Nguyen DV, et al. Structure-yeast α-glucosidase inhibitory activity relationship of 9-O-berberrubine carboxylates. Sci Rep. 2023 Nov 1;13 (1) :18865.