Ferroptosis-IN-3
Product Specifications
UNSPSC Description
Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC50: 8.6 nM in HT-1080 cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC50: 3.94 and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation[1].
Target Antigen
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ferroptosis-in-3.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C2=CC=C(O)C=C2)NN=C1C3=CC=C(Cl)C=C3
Molecular Weight
286.71
References & Citations
[1]Ying Danzhi, et al. Discovery of 4-hydroxyl pyrazole derivatives as potent ferroptosis inhibitors. European Journal of Medicinal Chemistry Available online 4 November 2023, 115913.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149670/Ferroptosis-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149670/
Clinical Information
No Development Reported
CAS Number
3017222-33-9
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