hCAIX/VII-IN-1
Product Specifications
UNSPSC Description
hCAIX/VII-IN-1 is a selective hCA VII/IX inhibitor. hCAIX/VII-IN-1 inhibit hCAⅠ, hCAⅡ, hCAⅣ, hCAⅦ and hCAⅨ with Ki values of 336.2 nM,185.8 nM, 1055 nM, 35.6 nM and 28.0 nM, respectively. hCAIX/VII-IN-1 can be used for the research of cancer and neurological diseases[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hcaix-vii-in-1.html
Solubility
10 mM in DMSO
Smiles
OB1OCC2=CC=C(C=C12)N3N=NC(COC4=CC=C(C=C4)F)=C3
Molecular Weight
325.10
References & Citations
[1]Nocentini A, et al. 6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography. J Med Chem. 2023 Jun 22;66(12):8118-8129.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149329/hCAIX-VII-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149329/
Clinical Information
No Development Reported
CAS Number
2990559-21-0
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