S1PR1 Radioligand 1
Product Specifications
UNSPSC Description
S1PR1 Radioligand 1(compound 6 h) is a specific S1PR1 radioligand with IC50 = 8.7 nM. S1PR1 Radioligand 1 has good brain uptake and can be used as a S1PR1-specific F-18 radiotracer for studying the function of S1PR1 in brain diseases[1].
Target Antigen
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s1pr1-radioligand-1.html
Solubility
10 mM in DMSO
Smiles
CN(CC1=C(C=C(C=C1)C2=NOC(C3=CC(C(F)(F)F)=C(C=C3)OCCF)=N2)F)CCCO
Molecular Weight
471.42
References & Citations
[1]Lin Qiu, et al. Discovery of a Promising Fluorine-18 Positron Emission Tomography Radiotracer for Imaging Sphingosine-1-Phosphate Receptor 1 in the Brain. J Med Chem. 2023 Mar 16.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149210/S1PR1-Radioligand-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149210/
Clinical Information
No Development Reported
CAS Number
2845249-11-6
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