HSV-1/HSV-2-IN-1
HSV-1/HSV-2-IN-1 (compound 7d) is a HSV-1 and HSV-2 inhibitor, with EC50s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and vaccinia virus in human embryonic lung fibroblast cell cultures[1].
Product Specifications
CAS Number
[2490468-31-8]
UNSPSC
12352005
Target
HSV; Orthopoxvirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hsv-1-hsv-2-in-1.html
Solubility
10 mM in DMSO
Smiles
CCN1C(/C(C2=CC(F)=CC=C21)=N\NC(NC3=CC=C(C=C3)C(F)(F)F)=S)=O
Molecular Formula
C18H14F4N4OS
Molecular Weight
410.39
References & Citations
[1]Sevinçli ZS, et, al. Synthesis, molecular modeling and antiviral activity of novel 5-fluoro-1H-indole-2,3-dione 3-thiosemicarbazones. Bioorg Chem. 2020 Nov;104:104202.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSV-1; HSV-2
Curated Selection
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