HSV-1/HSV-2-IN-1

HSV-1/HSV-2-IN-1 (compound 7d) is a HSV-1 and HSV-2 inhibitor, with EC50s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and vaccinia virus in human embryonic lung fibroblast cell cultures[1].

Product Specifications

CAS Number

[2490468-31-8]

UNSPSC

12352005

Target

HSV; Orthopoxvirus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hsv-1-hsv-2-in-1.html

Solubility

10 mM in DMSO

Smiles

CCN1C(/C(C2=CC(F)=CC=C21)=N\NC(NC3=CC=C(C=C3)C(F)(F)F)=S)=O

Molecular Formula

C18H14F4N4OS

Molecular Weight

410.39

References & Citations

[1]Sevinçli ZS, et, al. Synthesis, molecular modeling and antiviral activity of novel 5-fluoro-1H-indole-2,3-dione 3-thiosemicarbazones. Bioorg Chem. 2020 Nov;104:104202.