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Anti-MRSA agent 5

Anti-MRSA agent 5 (B14) is a potent MRSAagent with MIC50 values of 0.38 μg/mL and has low hERG activity with an IC50 values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquire bacterial resistance[1].

Product Specifications

CAS Number

[2490154-44-2]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/anti-mrsa-agent-5.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(C2CC2)C3=C(C=CC(NC4=NC=CC(OC5=CC=C(C)C(C)=C5)=N4)=C3)C1=O)O

Molecular Formula

C25H22N4O4

Molecular Weight

442.47

References & Citations

[1]Runzhe Songa, et al, Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity, Bioorg Chem. 2020 Oct;103:104176.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-149013/Anti-MRSA-agent-5-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-149013/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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