PROTAC c-Myc degrader-1
Product Specifications
UNSPSC Description
PROTAC c-Myc degrader-1 (Compound A153) is a multiple target protein degrader (PROTAC). PROTAC c-Myc degrader-1 effective degrades c-MYC, CK1α, GSPT1 and IKZF1/2/3 proteins in a variety of tumor cells. PROTAC c-Myc degrader-1 can be used for c-Myc high expression related disease research, such as cancer, cardiovascular and cerebrovascular diseases, and viral infection (Pink: c-Myc ligand (HY-168685); Blue: E3 ligase ligand (HY-W093472); Black: linker (HY-W015808))[1].
Target Antigen
Casein Kinase; c-Myc; PROTACs
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;PROTAC;Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/c-myc-inhibitor-7.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C2C(N(C3C(NC(CC3)=O)=O)CC2=C1)=O)NCC4=CC=C(CNC(CN5C6=C(C7=CC=CC=C75)C=CC=N6)=O)C=C4
Molecular Weight
614.65
References & Citations
[1]TONG YOUZHI, et al. 2,6-Dioxopiperidine compounds as c-Myc inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. WO2022268066. 2022.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148837/PROTAC-c-Myc-degrader-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148837/
Clinical Information
No Development Reported
CAS Number
2883535-99-5
Curated Selection
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