MCT1-IN-3
Product Specifications
UNSPSC Description
MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor with an IC50 value of 81.0 nM. MCT1-IN-3 has also significant inhibitivity against the multidrug transporter ABCB1. MCT1-IN-3 can be used for the research of cancer[1].
Target Antigen
Monocarboxylate Transporter; P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mct1-in-3.html
Solubility
10 mM in DMSO
Smiles
COC(/C(C#N)=C/C1=CN(C2=CC=CC=C12)CC(NC3=CC=C(C=C3)OC)=O)=O
Molecular Weight
389.40
References & Citations
[1]Sachin Puri, et al. Indole Derivatives as New Structural Class of Potent and Antiproliferative Inhibitors of Monocarboxylate Transporter 1 (MCT1; SLC16A1). J Med Chem. 2023 Jan 12;66(1):657-676.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148574/MCT1-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148574/
Clinical Information
No Development Reported
CAS Number
2878360-80-4
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