q-FTAA
Product Specifications
UNSPSC Description
q-FTAA binds to Aβ1-42 fibrils with EC50 values of 330-630, 300-500 nM for Aβ1-42 fibrils, alzheimer's disease PIB binding complex (ADPBC) , respectively. q-FTAA has the potential for the research of Alzheimer's disease (AD)[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/q-ftaa.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C2=CC(CC(O)=O)=C(C3=CC=C(C4=C(CC(O)=O)C=CS4)S3)S2)S1)O
Molecular Weight
490.59
References & Citations
[1]Bäck M, et al. Anionic Oligothiophenes Compete for Binding of X-34 but not PIB to Recombinant Aβ Amyloid Fibrils and Alzheimer's Disease Brain-Derived Aβ. Chemistry. 2016 Dec 19;22(51):18335-18338.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148547/q-FTAA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148547/
Clinical Information
No Development Reported
CAS Number
1352477-22-5
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