RL-0070933
RL-0070933 is a potent smo cilial modulator with an EC50 value of 0.02 µM. RL-0070933 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway[1].
Product Specifications
CAS Number
[301326-41-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Hedgehog; Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rl-0070933.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=CC=C(C2=CC=CC=C2)C=C1)C3=CC=C(O)C=C3
Molecular Formula
C20H16N2O2
Molecular Weight
316.35
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Yu Wang, et al. Modulators of hedgehog signaling pathway. US20130274233A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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