MM3122
Product Specifications
UNSPSC Description
MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor with an IC50 value of 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells[1].
Target Antigen
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mm3122.html
Purity
99.20
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(C2=NC3=CC=CC=C3S2)=O)=O)=O)=O)=O
Molecular Weight
665.76
References & Citations
[1]Matthew Mahoney, et al. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2108728118.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148072/MM3122-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148072/MM3122-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2574390-27-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1233309-01 0.02 mg (E-Coli)
Recombinant Clostridium beijerinckii UDP-N-acetylmuramate--L-alanine ligase (murC)
Ask
View Details 
MBS1233309-02 0.02 mg (Yeast)
Recombinant Clostridium beijerinckii UDP-N-acetylmuramate--L-alanine ligase (murC)
Ask
View Details 
MBS1233309-03 0.1 mg (E-Coli)
Recombinant Clostridium beijerinckii UDP-N-acetylmuramate--L-alanine ligase (murC)
Ask
View Details 
MBS1233309-04 0.1 mg (Yeast)
Recombinant Clostridium beijerinckii UDP-N-acetylmuramate--L-alanine ligase (murC)
Ask
View Details MBS1233309-05 0.02 mg (Baculovirus)
Recombinant Clostridium beijerinckii UDP-N-acetylmuramate--L-alanine ligase (murC)
Ask
View Details MBS1233309-06 0.02 mg (Mammalian-Cell)
Recombinant Clostridium beijerinckii UDP-N-acetylmuramate--L-alanine ligase (murC)
Ask
View Details