Ilaprazole sulfone
Ilaprazole sulfone is the major metabolite of Ilaprazole (HY-101664), is predominantly catalysed by CYP3A4/5. Ilaprazole (IY-81149) is an orally active proton pump inhibitor[1].
Product Specifications
CAS Number
[172152-37-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ilaprazole-sulfone.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2N1)(CC4=NC=CC(OC)=C4C)=O
Molecular Formula
C19H18N4O3S
Molecular Weight
382.44
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Seo KA, et al. Ilaprazole, a new proton pump inhibitor, is primarily metabolized to ilaprazole sulfone by CYP3A4 and 3A5. Xenobiotica. 2012 Mar;42 (3) :278-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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