Adenosine receptor inhibitor 2
Product Specifications
UNSPSC Description
Adenosine receptor inhibitor 2 (compound 14b) is a potent AR (adenosine receptor) inhibitor. Adenosine receptor inhibitor 2 shows dual affinity toward A1/A2A ARs with higher affinity for the A1- than the A2AAR. Adenosine receptor inhibitor 2 has Ki values of 52.2 nM for the A1AR and 167 nM for the A2AAR[1].
Target Antigen
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/adenosine-receptor-inhibitor-2.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CC)N(CC)C2=C(N(C)C(NCC3=CC=CC(Br)=C3)=N2)C1=O
Molecular Weight
406.28
References & Citations
[1]Załuski M, et al. 8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A2A receptors. Design, synthesis and biological evaluation. Bioorg Chem. 2020 Aug;101:104033.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147908/Adenosine-receptor-inhibitor-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147908/
Clinical Information
No Development Reported
CAS Number
2550401-76-6
Curated Selection
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