Tubulin inhibitor 29
Product Specifications
UNSPSC Description
Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-29.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(F)C=C1)(SC2=CC=C(F)C=C2)=O
Molecular Weight
286.32
References & Citations
[1]Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147888/Tubulin-inhibitor-29-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147888/
Clinical Information
No Development Reported
CAS Number
2905-15-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal ULBP-1 Antibody (170818) [DyLight 650]](https://cdn.genprice.uk/genprice/genprice4.png)
![Rabbit Polyclonal SDF2 Antibody [DyLight 650]](https://cdn.genprice.uk/genprice/genprice3.png)
