MK2-IN-4

MK2-IN-4 is a MAPKAPK2 (MK2) inhibitor with an IC50 value of 45 nM. MK2-IN-4 can be used in the research of cancer, inflammation, immunology[1].

Product Specifications

CAS Number

[1105658-32-9]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

MAPKAPK2 (MK2)

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mk2-in-4.html

Solubility

10 mM in DMSO

Smiles

O=C1NCC2(CC2)C3=C1C4=C(C5=CC(C6=CC(OCCN7C)=C7C=C6)=NC=C5CC4)N3

Molecular Formula

C25H24N4O2

Molecular Weight

412.48

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Schlapbach, et al. Heterocyclic compounds useful as MK2 inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. Patent WO2009010488.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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