Coronastat

Coronastat is a potent inhibitor of the SARS-CoV-2 3CL protease. The SARS-CoV-2 3CL protease is a critical agent target for small molecule COVID-19, given its likely agentgability and essentiality in the viral maturation and replication cycle[1].

Product Specifications

CAS Number

[2922281-15-8]

Product Name Alternative

NK01-63

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/coronastat.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

OC(S(=O)(O[Na])=O)[C@H](C[C@@H]1CCNC1=O)NC([C@H](CC(C)C)NC(OCC2=CC(C(F)(F)F)=CC=C2)=O)=O

Molecular Formula

C22H29F3N3NaO8S

Molecular Weight

575.53

References & Citations

[1]Liu H, et al. Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nat Commun. 2022;13 (1) :1891.