(S) -GSK1379725A
(S) -GSK1379725A (compound AU1) is a selective bromodomain and PHD finger containing transcription factor (BPTF) bromodomain inhibitor with a Kd of 2.8 μM. (S) -GSK1379725A shows to be selective for BPTF over BRD4 bromodomain. (S) -GSK1379725A shows antimalarial activity[1].
Product Specifications
CAS Number
[2359618-49-6]
UNSPSC
12352005
Target
Epigenetic Reader Domain; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/s-gsk1379725a.html
Solubility
10 mM in DMSO
Smiles
COC(C1=CC=CC(NC(N[C@@H](CC2)CN2C3=NC(NC4=CC=C(C=C4)F)=NC=C3)=O)=C1)=O
Molecular Formula
C23H23FN6O3
Molecular Weight
450.47
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
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