DX3-234
Product Specifications
UNSPSC Description
DX3-234 is an oxidative phosphorylation (OXPHOS) inhibitor. DX3-234 shows significant tumor suppression in the Pan02 syngeneic model of pancreatic cancer[1].
Target Antigen
Mitochondrial Metabolism; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dx3-234.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C=C1)S(=O)(N2C[C@@H](CCC2)C(N3CCN(CC3)C4=NC(C(C)C)=NO4)=O)=O)(C5CCC5)=O
Molecular Weight
565.71
References & Citations
[1]Xue D, et al. Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors. J Med Chem. 2022;65(1):343-368.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145306/DX3-234-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145306/
Clinical Information
No Development Reported
CAS Number
2941323-59-5
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