AChE/BChE-IN-2

AChE/BChE-IN-2 (Compound 13b) is a potent inhibitor of AChE/BChE (AChE IC50 = 0.96 ± 0.14 µM, BChE IC50 = 1.23 ± 0.23 µM) . AChE/BChE-IN-2 has the potential for the research of AD diseases[1].

Product Specifications

CAS Number

[2761991-42-6]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-bche-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC(NCCC1=CNC2=C1C=C(OC)C=C2)=O)/C=C/C3=CC=C(O)C(OC)=C3

Molecular Formula

C23H25N3O5

Molecular Weight

423.46

References & Citations

[1]Singh YP, et al. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease. Bioorg Med Chem. 2021 Sep 15;46:116385. doi: 10.1016/j.bmc.2021.116385.