mGlu4 receptor agonist 1
Product Specifications
UNSPSC Description
mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect[1].
Target Antigen
mGluR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mglu4-receptor-agonist-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(NC(C2=CC=CC=N2)=O)=CC=C1C3=NOC(C4=C(C=CC=C4)Cl)=N3
Molecular Weight
390.82
References & Citations
[1]Stankiewicz A, et al. New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties. J Enzyme Inhib Med Chem. 2022 Dec;37(1):211-225.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144698/mGlu4-receptor-agonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144698/
Clinical Information
No Development Reported
CAS Number
1678501-16-0
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