(2R,4R) -LY3372689

O-GlcNAcase-IN-4 is a O-GlcNAcase inhibitor extracted from patent WO2018140299A1 Formulaic Ic. O-GlcNAcase-IN-4 can be used for the research of neurodegenerative diseases and disorders, such as Alzheimer's disease[1].

Product Specifications

UNSPSC

12352005

Target

OGA

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2r-4r-ly3372689.html

Solubility

10 mM in DMSO

Smiles

CC(NC1=NC(F)=C(S1)CN2[C@@H](C[C@@H](CC2)OCC3=NOC(C)=N3)C)=O

Molecular Formula

C16H22FN5O3S

Molecular Weight

383.44

References & Citations

[1]Dreyfus NJF, et, al. N-[4-fluoro-5-[[ (2s,4s) -2-methyl-4-[ (5-methyl-1,2,4-oxadiazol-3-yl) methoxy]-1-piperidyl]methyl]thiazol-2-yl]acetamide as oga inhibitor. WO2018140299A1.