Aβ-IN-1
Product Specifications
UNSPSC Description
Aβ-IN-1 is a Aβ1–42 aggregation inhibitor. Aβ-IN-1 inhibits Aβ1-42 self-aggregation in vitro by delaying the exponential growth phase or reduces the quantity of fibrils in the steady state. Aβ-IN-1 can be used for the research of conformational disorders[1].
Target Antigen
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aβ-in-1.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@](CC=C1C4=C(C)C5=CC=CC=C5N=C4CC2)([H])[C@@]6([H])[C@](CC3)([C@@](CC6)([H])[C@H](C)CCCC(C)C)C
Molecular Weight
483.77
References & Citations
[1]Hélio M T Albuquerque, et al. Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Med Chem Lett. 2022 Feb 14;13(3):443-448.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144326/Aβ-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144326/
Clinical Information
No Development Reported
CAS Number
2766509-32-2
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