DNA-PK-IN-4
Product Specifications
UNSPSC Description
DNA-PK-IN-4 is a potent inhibitor of DNA-PK. DNA-PK-IN-4 is a imidazolinone derivative compound. DNA-PK-IN-4 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021209055A1, compound 27)[1].
Target Antigen
DNA-PK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dna-pk-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(NC)C1=CC=C(NC2=NC=C3N(C)C(N(C4CCOCC4)C3=N2)=O)C(C)=C1
Molecular Weight
396.44
References & Citations
[1]Yonggang Wei, et al. Imidazolinone derivatives and their applications in medicine. Patent WO2021209055A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144037/DNA-PK-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144037/
Clinical Information
No Development Reported
CAS Number
2722645-10-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS650058-01 0.02 mg
Macrophage, Monocyte Chemotactic Protein-1, Recombinant, Human (Monocyte Chemotactic Protein 1, MCP1, MCP-1, C-C Motif Chemokine 2, Chemokine (C-C Motif) Ligand 2, CCL2, GDCF-2, HC11, HSMCR30, MGC9434, Monocyte Chemoattractant Protein 1, Monocyte Chemotac
Ask
View Details MBS650058-02 5x 0.02 mg
Macrophage, Monocyte Chemotactic Protein-1, Recombinant, Human (Monocyte Chemotactic Protein 1, MCP1, MCP-1, C-C Motif Chemokine 2, Chemokine (C-C Motif) Ligand 2, CCL2, GDCF-2, HC11, HSMCR30, MGC9434, Monocyte Chemoattractant Protein 1, Monocyte Chemotac
Ask
View Details 
