MK-4965

MK-4965 is a nonnucleoside reverse transcriptase inhibitor (NNRTI) . MK-4965 displays excellent activities against not only HIV-1 wild-type (WT) virus but also against a broad panel of NNRTI-resistant viruses and can be used for the research of HIV-1 infection[1].

Product Specifications

CAS Number

[920035-77-4]

UNSPSC

12352005

Hazard Statement

H302

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mk-4965.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC(Cl)=CC(OC2=CC(OCC3=NNC4=NC(N)=CC=C43)=CC=C2Cl)=C1

Molecular Formula

C20H13Cl2N5O2

Molecular Weight

426.26

Precautions

P264-P270-P330-P501

References & Citations

[1]Lai MT, et al. Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2009 Jun;53 (6) :2424-31.