DNA-PK-IN-2

DNA-PK-IN-2 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) . DNA-PK-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2021136462A1, compound 1) [1].

Product Specifications

CAS Number

[2665720-22-7]

UNSPSC

12352005

Target

DNA-PK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dna-pk-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C)C2=CN=C(NC3=CC4=C(C=C3C)OCC4)N=C2N1C5CCOCC5

Molecular Formula

C20H23N5O3

Molecular Weight

381.43

References & Citations

[1]Yonggang Wei, et al. Furan derivatives and their applications in medicine. Patent WO2021136462A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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