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HL-PEG2k

HL-PEG2k is a second near-infrared Ru (II) polypyridyl complex. HL-PEG2k exhibits a wavelength bathochromic shift, enhanced photothermal conversion efficiency (41.77%), and an antineoplastic effect against glioma. HL-PEG2k displays a superior biocompatibility and thus can be a potential theranostic platform to combat the growth and recurrence of tumors[1].

Product Specifications

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hl-peg2k.html

Solubility

10 mM in DMSO

Smiles

O=C(N[PEG2000]OC)CCC(C=C1)=CC=C1N(C2=CC=CC=C2)C(C=C3)=CC=C3C4=C(N=S=N5)C5=C(C(C=C6)=CC=C6N(C7=CC=C(CCC(N[PEG2000]OC)=O)C=C7)C8=CC=CC=C8)C9=NC%10=C(C=CC=[N]%11[Ru]%12%13([N]%14=CC=CC=C%14C%15=[N]%12C=CC=C%15)([N]%16=C(C%17=CC=CC=[N]%17%13)C=CC=C%16)[N]%18=CC=C%19)C%11=C%18C%19=C%10N=C94.[2+].[2Cl-]

References & Citations

[1]Liu Y, et al. A Second Near-Infrared Ru (II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy. J Med Chem. 2022;65 (3) :2225-2237.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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