Milrinone (lactate)

Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock[1][2].

Product Specifications

CAS Number

[100286-97-3]

Product Name Alternative

Win 47203 (lactate)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/milrinone-lactate.html

Solubility

10 mM in DMSO

Smiles

OC(C)C(O)=O.CC(N1)=C(C2=CC=NC=C2)C=C(C#N)C1=O.[x]

Molecular Formula

C12H9N3O.xC3H6O3

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Bregagnollo EA, et al. Assessment of inotropic and vasodilating effects of milrinone lactate in patients with dilated cardiomyopathy and severe heart failure. Arq Bras Cardiol. 1999 Feb;72 (2) :149-60.|[2]Meyer S, et al. The role of milrinone in children with cardiovascular compromise: review of the literature. Wien Med Wochenschr. 2011 Apr;161 (7-8) :184-91.