Adenosine receptor antagonist 1

Adenosine receptor antagonist 1 is a A2aR-selective antagonist with an IC50 of 0.29 nM and displays 14-fold more selective for A2aR than A2bR.

Product Specifications

CAS Number

[2682930-40-9]

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/adenosine-receptor-antagonist-1.html

Solubility

10 mM in DMSO

Smiles

NC1=NC(C2=CC=CC=C2)=C(C3=NC(CC4=C(C=C(C=N4)F)Cl)=NN13)C5=CNC(C=C5)=O

Molecular Formula

C22H15ClFN7O

Molecular Weight

447.85

References & Citations

[1]Lamb ML, et al. Triazole compounds as adenosine receptor antagonists. WO2021156439A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Adenosine A2A receptor (A2AR)

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS648475-01 0.2 mL

FSCB, CT (FSCB, C14orf155, Fibrous sheath CABYR-binding protein)

Ask

View Details

MBS648475-02 5x 0.2 mL

FSCB, CT (FSCB, C14orf155, Fibrous sheath CABYR-binding protein)

Ask

View Details

RC215623L4V 200 µL

glucose 6 phosphatase, catalytic subunit (G6PC) (NM_000151) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

A303-870A-T 10 µg

Goal anli-HdmX/MDM4 Antibody, Affinily Purified

Ask

View Details

AFG-ELL-0031 > 1x 10^6 Cells / Vial

Human Acute Myeloid Leukemia Cells [KG-1a]

Ask

View Details

TA505998 100 µL

Parvin alpha (PARVA) Mouse Monoclonal Antibody [Clone ID: OTI3G9]

Ask

View Details