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(S, E) -TCO2-PEG8-acid

(S) -TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid (COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S) -TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S) -TCO-PEG8-acid is longer than (S) -TCO-PEG3-acid[1].

Product Specifications

UNSPSC

12352211

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-e-tco2-peg8-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)O[C@@H]1/C=C/CCCCC1

Molecular Formula

C28H51NO12

Molecular Weight

593.70

References & Citations

[1]Dion Voerman, et al. Synthetic Semiflexible and Bioactive Brushes. Biomacromolecules. 2019 Jul 8;20 (7) :2587-2597.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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