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(S,E)-TCO2-PEG8-acid

Product Specifications

UNSPSC Description

(S)-TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S)-TCO-PEG8-acid is longer than (S)-TCO-PEG3-acid[1].

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

cancer

Assay Protocol

https://www.medchemexpress.com/s-e-tco2-peg8-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)O[C@@H]1/C=C/CCCCC1

Molecular Weight

593.70

References & Citations

[1]Dion Voerman, et al. Synthetic Semiflexible and Bioactive Brushes. Biomacromolecules. 2019 Jul 8;20(7):2587-2597.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-141161A/S-E-TCO2-PEG8-acid-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-141161A/

Clinical Information

No Development Reported

Curated Selection

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