(S,E)-TCO2-PEG8-acid
Product Specifications
UNSPSC Description
(S)-TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S)-TCO-PEG8-acid is longer than (S)-TCO-PEG3-acid[1].
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/s-e-tco2-peg8-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)O[C@@H]1/C=C/CCCCC1
Molecular Weight
593.70
References & Citations
[1]Dion Voerman, et al. Synthetic Semiflexible and Bioactive Brushes. Biomacromolecules. 2019 Jul 8;20(7):2587-2597.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141161A/S-E-TCO2-PEG8-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141161A/
Clinical Information
No Development Reported
Curated Selection
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