(S, E) -TCO2-PEG8-acid
(S) -TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid (COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S) -TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S) -TCO-PEG8-acid is longer than (S) -TCO-PEG3-acid[1].
Product Specifications
UNSPSC
12352211
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-e-tco2-peg8-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)O[C@@H]1/C=C/CCCCC1
Molecular Formula
C28H51NO12
Molecular Weight
593.70
References & Citations
[1]Dion Voerman, et al. Synthetic Semiflexible and Bioactive Brushes. Biomacromolecules. 2019 Jul 8;20 (7) :2587-2597.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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