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N-Desthiobiotin-N-bis(PEG4-NHS ester)

Product Specifications

UNSPSC Description

N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-desthiobiotin-n-bis-peg4-nhs-ester.html

Solubility

10 mM in DMSO

Smiles

O=C(CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(ON(C1=O)C(CC1)=O)=O)C(CCCCC[C@@H](NC2=O)[C@@H](N2)C)=O)ON(C3=O)C(CC3)=O

Molecular Weight

903.97

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140583/N-Desthiobiotin-N-bis-PEG4-NHS-ester-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140583/

Clinical Information

No Development Reported

CAS Number

2353409-61-5

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