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Azidoethyl-SS-PEG2-Boc

Product Specifications

UNSPSC Description

Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azidoethyl-SS-PEG2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/azidoethyl-ss-peg2-boc.html

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)CCOCCOCCSSCCN=[N+]=[N-]

Molecular Weight

351.49

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140107/Azidoethyl-SS-PEG2-Boc-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140107/

Clinical Information

No Development Reported

CAS Number

2144777-83-1

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