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Antibacterial agent 63

Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.

Product Specifications

CAS Number

[2910919-43-4]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-63.html

Solubility

10 mM in DMSO

Smiles

NC1=NC(/C(C(N[C@@H]2C(N(S(O)(=O)=O)[C@H]2C)=O)=O)=N/OC(C(NCCNC(CN(C(C3=CC=CC(O)=C3O)=O)CCCCNC(C4=CC=CC(O)=C4O)=O)=O)=O)(C)C)=CS1

Molecular Formula

C35H43N9O14S2

Molecular Weight

877.90

References & Citations

[1]Liu R, et al. Conjugation of Aztreonam, a Synthetic Monocyclic β-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria. ACS Infect Dis. 2021 Nov 12;7 (11) :2979-2986.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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