AT-9010

AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication) . AT-9010 can inhibit SARS-CoV-2 replication[1].

Product Specifications

CAS Number

[1261253-79-5]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/at-9010.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@](F)(C)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1COP(O)(OP(OP(O)(O)=O)(O)=O)=O

Molecular Formula

C11H17FN5O13P3

Molecular Weight

539.20

References & Citations

[1]Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.