Etbicyphat-13C3
Etbicyphat-13C3 is the 13C labeled Etbicyphat (HY-139145) . Etbicyphat is a potent GABA (A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA (A) -benzodiazepine receptors[1][2].
Product Specifications
CAS Number
[2300178-69-0]
Product Name Alternative
Trimethylopropane phosphate-13C3
UNSPSC
12352005
Target
GABA Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/etbicyphat-13c3.html
Solubility
10 mM in DMSO
Smiles
CC[13C](CO1)([13CH2]O2)[13CH2]O[P]12=O
Molecular Formula
C3 13C3H11O4P
Molecular Weight
181.10
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Rijal SO, et al. Dissociation constants for GABA (A) receptor antagonists determined with neuronal networks on microelectrode arrays. J Neurosci Methods. 2008 Aug 30;173 (2) :183-92.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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